CovidV1, Main, Exploration, bibRecord, 000125

Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia.

Identifieur interne : 000125 ( Main/Exploration ); précédent : 000124; suivant : 000126

Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia.

Auteurs : Feng Pan [Royaume-Uni] ; Tianhe Ye [Royaume-Uni] ; Peng Sun [Royaume-Uni] ; Shan Gui [Royaume-Uni] ; Bo Liang [Royaume-Uni] ; Lingli Li [Royaume-Uni] ; Dandan Zheng [Royaume-Uni] ; Jiazheng Wang [Royaume-Uni] ; Richard L. Hesketh [Royaume-Uni] ; Lian Yang [Royaume-Uni] ; Chuansheng Zheng [Royaume-Uni]

Source :

Radiology [ 1527-1315 ] ; 2020.

RBID : pubmed:32053470

Abstract

Background Chest CT is used to assess the severity of lung involvement in COVID-19 pneumonia. Purpose To determine the change in chest CT findings associated with COVID-19 pneumonia from initial diagnosis until patient recovery. Materials and Methods This retrospective review included patients with RT-PCR confirmed COVID-19 infection presenting between 12 January 2020 to 6 February 2020. Patients with severe respiratory distress and/ or oxygen requirement at any time during the disease course were excluded. Repeat Chest CT was obtained at approximately 4 day intervals. The total CT score was the sum of lung involvement (5 lobes, score 1-5 for each lobe, range, 0 none, 25 maximum) was determined. Results Twenty one patients (6 males and 15 females, age 25-63 years) with confirmed COVID-19 pneumonia were evaluated. These patients under went a total of 82 pulmonary CT scans with a mean interval of 4±1 days (range: 1-8 days). All patients were discharged after a mean hospitalized period of 17±4 days (range: 11-26 days). Maximum lung involved peaked at approximately 10 days (with the calculated total CT score of 6) from the onset of initial symptoms (R2=0.25), p<0.001). Based on quartiles of patients from day 0 to day 26 involvement, 4 stages of lung CT were defined: Stage 1 (0-4 days): ground glass opacities (GGO) in 18/24 (75%) patients with the total CT score of 2±2; (2)Stage-2 (5-8d days): increased crazy-paving pattern 9/17 patients (53%) with a increase in total CT score (6±4, p=0.002); (3) Stage-3 (9-13days): consolidation 19/21 (91%) patients with the peak of total CT score (7±4); (4) Stage-4 (≥14 days): gradual resolution of consolidation 15/20 (75%) patients with a decreased total CT score (6±4) without crazy-paving pattern. Conclusion In patients recovering from COVID-19 pneumonia (without severe respiratory distress during the disease course), lung abnormalities on chest CT showed greatest severity approximately 10 days after initial onset of symptoms.

DOI: 10.1148/radiol.2020200370
PubMed: 32053470

Affiliations:

Royaume-Uni

Le document en format XML

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<author><name sortKey="Pan, Feng" sort="Pan, Feng" uniqKey="Pan F" first="Feng" last="Pan">Feng Pan</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
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<author><name sortKey="Ye, Tianhe" sort="Ye, Tianhe" uniqKey="Ye T" first="Tianhe" last="Ye">Tianhe Ye</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
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<author><name sortKey="Sun, Peng" sort="Sun, Peng" uniqKey="Sun P" first="Peng" last="Sun">Peng Sun</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
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<author><name sortKey="Gui, Shan" sort="Gui, Shan" uniqKey="Gui S" first="Shan" last="Gui">Shan Gui</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
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<author><name sortKey="Liang, Bo" sort="Liang, Bo" uniqKey="Liang B" first="Bo" last="Liang">Bo Liang</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
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<author><name sortKey="Li, Lingli" sort="Li, Lingli" uniqKey="Li L" first="Lingli" last="Li">Lingli Li</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
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</author>
<author><name sortKey="Zheng, Dandan" sort="Zheng, Dandan" uniqKey="Zheng D" first="Dandan" last="Zheng">Dandan Zheng</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
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</author>
<author><name sortKey="Wang, Jiazheng" sort="Wang, Jiazheng" uniqKey="Wang J" first="Jiazheng" last="Wang">Jiazheng Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hesketh, Richard L" sort="Hesketh, Richard L" uniqKey="Hesketh R" first="Richard L" last="Hesketh">Richard L. Hesketh</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
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</author>
<author><name sortKey="Yang, Lian" sort="Yang, Lian" uniqKey="Yang L" first="Lian" last="Yang">Lian Yang</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
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<author><name sortKey="Zheng, Chuansheng" sort="Zheng, Chuansheng" uniqKey="Zheng C" first="Chuansheng" last="Zheng">Chuansheng Zheng</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia.</title>
<author><name sortKey="Pan, Feng" sort="Pan, Feng" uniqKey="Pan F" first="Feng" last="Pan">Feng Pan</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
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</author>
<author><name sortKey="Ye, Tianhe" sort="Ye, Tianhe" uniqKey="Ye T" first="Tianhe" last="Ye">Tianhe Ye</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sun, Peng" sort="Sun, Peng" uniqKey="Sun P" first="Peng" last="Sun">Peng Sun</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gui, Shan" sort="Gui, Shan" uniqKey="Gui S" first="Shan" last="Gui">Shan Gui</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liang, Bo" sort="Liang, Bo" uniqKey="Liang B" first="Bo" last="Liang">Bo Liang</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, Lingli" sort="Li, Lingli" uniqKey="Li L" first="Lingli" last="Li">Lingli Li</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zheng, Dandan" sort="Zheng, Dandan" uniqKey="Zheng D" first="Dandan" last="Zheng">Dandan Zheng</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wang, Jiazheng" sort="Wang, Jiazheng" uniqKey="Wang J" first="Jiazheng" last="Wang">Jiazheng Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hesketh, Richard L" sort="Hesketh, Richard L" uniqKey="Hesketh R" first="Richard L" last="Hesketh">Richard L. Hesketh</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yang, Lian" sort="Yang, Lian" uniqKey="Yang L" first="Lian" last="Yang">Lian Yang</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zheng, Chuansheng" sort="Zheng, Chuansheng" uniqKey="Zheng C" first="Chuansheng" last="Zheng">Chuansheng Zheng</name>
<affiliation wicri:level="1"><nlm:affiliation>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU, UK (R.L.H).</nlm:affiliation>
<country>Royaume-Uni</country>
<wicri:regionArea>From the Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (F.P., T.Y., S.G., B.L., L.L., L.Y., C.Z); Department of Radiology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, China (F.P., T.Y.); Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1277, Wuhan, 430022, China (P.S.); Department of Radiology, MSC Clinical& Technical Solutions, Philips Healthcare, Beijing, 100000, China (D.Z., J.W.); Department of Radiology, University College London Hospital, 235, Euston Road, London, NW1 2BU</wicri:regionArea>
<wicri:noRegion>NW1 2BU</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Radiology</title>
<idno type="eISSN">1527-1315</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background Chest CT is used to assess the severity of lung involvement in COVID-19 pneumonia. Purpose To determine the change in chest CT findings associated with COVID-19 pneumonia from initial diagnosis until patient recovery. Materials and Methods This retrospective review included patients with RT-PCR confirmed COVID-19 infection presenting between 12 January 2020 to 6 February 2020. Patients with severe respiratory distress and/ or oxygen requirement at any time during the disease course were excluded. Repeat Chest CT was obtained at approximately 4 day intervals. The total CT score was the sum of lung involvement (5 lobes, score 1-5 for each lobe, range, 0 none, 25 maximum) was determined. Results Twenty one patients (6 males and 15 females, age 25-63 years) with confirmed COVID-19 pneumonia were evaluated. These patients under went a total of 82 pulmonary CT scans with a mean interval of 4±1 days (range: 1-8 days). All patients were discharged after a mean hospitalized period of 17±4 days (range: 11-26 days). Maximum lung involved peaked at approximately 10 days (with the calculated total CT score of 6) from the onset of initial symptoms (R2=0.25), p<0.001). Based on quartiles of patients from day 0 to day 26 involvement, 4 stages of lung CT were defined: Stage 1 (0-4 days): ground glass opacities (GGO) in 18/24 (75%) patients with the total CT score of 2±2; (2)Stage-2 (5-8d days): increased crazy-paving pattern 9/17 patients (53%) with a increase in total CT score (6±4, p=0.002); (3) Stage-3 (9-13days): consolidation 19/21 (91%) patients with the peak of total CT score (7±4); (4) Stage-4 (≥14 days): gradual resolution of consolidation 15/20 (75%) patients with a decreased total CT score (6±4) without crazy-paving pattern. Conclusion In patients recovering from COVID-19 pneumonia (without severe respiratory distress during the disease course), lung abnormalities on chest CT showed greatest severity approximately 10 days after initial onset of symptoms.</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Pan, Feng" sort="Pan, Feng" uniqKey="Pan F" first="Feng" last="Pan">Feng Pan</name>
</noRegion>
<name sortKey="Gui, Shan" sort="Gui, Shan" uniqKey="Gui S" first="Shan" last="Gui">Shan Gui</name>
<name sortKey="Hesketh, Richard L" sort="Hesketh, Richard L" uniqKey="Hesketh R" first="Richard L" last="Hesketh">Richard L. Hesketh</name>
<name sortKey="Li, Lingli" sort="Li, Lingli" uniqKey="Li L" first="Lingli" last="Li">Lingli Li</name>
<name sortKey="Liang, Bo" sort="Liang, Bo" uniqKey="Liang B" first="Bo" last="Liang">Bo Liang</name>
<name sortKey="Sun, Peng" sort="Sun, Peng" uniqKey="Sun P" first="Peng" last="Sun">Peng Sun</name>
<name sortKey="Wang, Jiazheng" sort="Wang, Jiazheng" uniqKey="Wang J" first="Jiazheng" last="Wang">Jiazheng Wang</name>
<name sortKey="Yang, Lian" sort="Yang, Lian" uniqKey="Yang L" first="Lian" last="Yang">Lian Yang</name>
<name sortKey="Ye, Tianhe" sort="Ye, Tianhe" uniqKey="Ye T" first="Tianhe" last="Ye">Tianhe Ye</name>
<name sortKey="Zheng, Chuansheng" sort="Zheng, Chuansheng" uniqKey="Zheng C" first="Chuansheng" last="Zheng">Chuansheng Zheng</name>
<name sortKey="Zheng, Dandan" sort="Zheng, Dandan" uniqKey="Zheng D" first="Dandan" last="Zheng">Dandan Zheng</name>
</country>
</tree>
</affiliations>
</record>

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Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia.

Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia.

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